The principle of freeze dryer is to make use of the sublimation principle, so that the water in the pre-frozen material, without ice melting, directly to ice sublimation as water vapor is removed, so as to achieve the purpose of drying. When drying at low temperature, the loss of some volatile components in the material is very small, the volume is almost unchanged, the original structure is maintained, there will be no concentration phenomenon, suitable for some chemical products, drugs and food drying. Therefore, its application is mainly used in biology, medicine, food, nutrition and health products and other fields. The freeze dryer system consists of refrigeration system, vacuum system, control system and circulation system.
Freeze-drying is a method of freezing water-bearing material into solid state and then sublimating the water from solid state to gas state to remove the water and preserve the material. Because the solid composition is supported by solid ice in its place, the biological and chemical structure and activity of the product are preserved.
Freeze-drying machine is widely used in the fields of medical and health, disease prevention and control, food hygiene, biopharmaceutical, environmental monitoring and various biological laboratories. Establish calibration specification for freeze dryer to improve drying speed and retain the integrity of biological and chemical structure and activity of samples.
Calibration environmental conditions:
1. Ambient temperature :(10 ~ 30)℃;
2. Relative humidity: ≤70%;
3. Others: Indoor should have good dustproof measures, instruments should be far away from vibration, electromagnetic interference.
1. Calibration device: multimeter, minimum resolution: temperature ≤1 ℃; The maximum allowable error is ±0.25%.
2. Vacuum gauge: minimum resolution: vacuum ≤ 0.01Pka; The maximum allowable error is ±0.05%.
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